Scientists have had a great outcome on rats and hopefully it will be just as effective on humans!
Why people with spinal cord injury become immune compromised is unknown, but previous research has found that a disorder called autonomic dysreflexia (AD) can cause immune suppression. This potentially dangerous complication of high-level spinal cord injury is characterized by exaggerated activation of spinal autonomic reflexes. This, in turn, can cause an abrupt onset of excessively high blood pressure that can cause pulmonary embolism, stroke and even death. In order to examine this condition a bit more closely, the scientists looked at its development in mice. They found that autonomic dysreflexia develops spontaneously in spinal cord injured mice and becomes more frequent as time passes. They also discovered that everyday occurrences that activate normal spinal autonomic reflexes become hyperactive and suppress immune function.
Spinal cord injuries can be devastating for patients. Now, scientists have discovered that it's possible to restore immune function in spinal injured mice, which could pave the way for future research.
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