Brain-computer interfaces (BCIs) and neural devices have the potential to improve quality of life after spinal cord injury. BCIs have progressed from animal studies to human trials, including ongoing work using brain activity to control Functional Electrical Stimulation (FES) of paralyzed hand muscles. Another promising method for re-animation of paralyzed limbs is intraspinal stimulation. Intraspinal stimulation activates muscles with minimal fatigue and often in functional synergies, making it an ideal candidate for brain-control of stimulation with the goal of restoring hand and arm function after spinal cord injury.