Inspired Spinal Cord Injury Support Forum

rebeccawio
New Member

Posts: 5
Post Likes Received: 9
Date Joined: January 2015

Member is: Offline
Send PM

Olfactory Ensheathing Cell Transplant Mar 30, 2015 4:46:00 GMT -8

Quote

Post by rebeccawio on Mar 30, 2015 4:46:00 GMT -8

Hey there!
Within the last year, there has been a clinical trial suggesting that by transplanting cells from inside the nose, olfactory ensheathing glial cells, above and below the spinal cord injury site that regeneration and some recovery is possible. The most prominent case in the media is with Darek Fidyka who sustained a T9, complete spinal cord injury leaving an 8 mm gap in his spinal cord. Fidyka underwent the OEC transplant and started recovering function and sensation in areas that were previously paralysed.

The science behind choosing the OECs for the transplant is that they are similar to stem cells in the sense that they can adapt to their environment, OECs have also been speculated a strong candidate for this procedure because they clean up dead cells in the area and replace them with new ones, encourage nerve growth, and can be acquired from within the individual relatively easily.

I am wondering what your take is on this type of procedure for potential therapy; recovery and regeneration of the spinal cord. Do you think it seems promising? are you sceptical? If you want some more information on OECs and Fidyka's case, take a look at this blog article! walkitoffrecovery.org/2015/01/08/olfactory-ensheathing-cells-and-spinal-cord-recovery/#more-968

DJ likes this

joemonte
Member

Posts: 172

Post Likes Received: 257
Date Joined: July 2013
Injury: T-10 Complete Asia "A"
Date Injured: March 10, 2007

Member is: Offline
Send PM

Olfactory Ensheathing Cell Transplant Mar 30, 2015 5:53:02 GMT -8

Quote

Post by joemonte on Mar 30, 2015 5:53:02 GMT -8

I believe all the research and clinical studies are promising. sooner or later we will hear positive news. Once the data is published in the medical journal, we then know are day will come. I have seen a very strong awareness in research and clinical studies the last two years. I never seen this much back six or more years ago. I feel that is very good for all of us. I keep the faith and hope that someday we will regain what we have lost. A lot of research can be skeptical but if it is published in the medical journal , then it is promising. It is the FDA's bible of medicine. I believe we are very close for nerve connection and the firing up of Lower motor neurons. I would be happy with that to regain bowel and blatter. This would be a major stepping stone for all of us. Best to all and thanks for the article.

DJ, wavewolf, and 2 more like this

DJ Administrator STAFF Posts: 8,162 Post Likes Received: 2,829 Date Joined: July 2013 Injury: C6 - ASIA B Date Injured: June 2011 Member is: Offline Send PM	Olfactory Ensheathing Cell Transplant Mar 30, 2015 13:59:21 GMT -8 Quote Select Post Deselect Post Link to Post Back to Top Post by DJ on Mar 30, 2015 13:59:21 GMT -8 Welcome rebeccawio
	rebeccawio likes this

wavewolf
Advanced Member

Posts: 1,407

Post Likes Received: 1,159
Date Joined: July 2013
Injury: T9 incomplete + other neurological
Date Injured: 10 February 2009

Member is: Offline
Send PM

Olfactory Ensheathing Cell Transplant Apr 1, 2015 23:06:18 GMT -8

Quote

Post by wavewolf on Apr 1, 2015 23:06:18 GMT -8

Welcome to the forum, rebeccawio. I had read of this here: www.nationalrighttolifenews.org/news/2014/10/cells-transplanted-from-patients-own-nose-help-paralyzed-man-walk/. Very exciting prospect! Bit more info on Darek Fidyka at en.wikipedia.org/wiki/Darek_Fidyka. I have also heard in SCI forums great praise for the work you are doing at Walk It Off!

DJ, Europedude, and 1 more like this

Hoea ra!

rebeccawio
New Member

Posts: 5
Post Likes Received: 9
Date Joined: January 2015

Member is: Offline
Send PM

Olfactory Ensheathing Cell Transplant Apr 9, 2015 8:06:27 GMT -8

Quote

Post by rebeccawio on Apr 9, 2015 8:06:27 GMT -8

Thanks for the kind welcoming!
We are always very excited at Walk It Off to hear about new break throughs in the SCI recovery and rehabilitation field. In Fidyka's case, he has experienced some very impressive gains which we hope can be duplicated in the near future with more SCI cases.

Thanks for posting more informative links on the topic, wavewolf,. It's always good to be up to date!

DJ and wavewolf like this

capybara
New Member

Posts: 7

Post Likes Received: 15
Date Joined: March 2015
Injury: C6 incomplete
Date Injured: April 2014

Member is: Offline
Send PM

Olfactory Ensheathing Cell Transplant Apr 15, 2015 13:08:02 GMT -8

Quote

Post by capybara on Apr 15, 2015 13:08:02 GMT -8

I read some of the articles about him, it sounds like they use the OECs in conjunction with a nerve grafted from somewhere else in the body to bridge a gap in the spinal cord. Is there any application of this for incomplete injuries? i.e. in someone who has a damaged cord but no observable gap?

DJ likes this

Lαrα
Global Moderator

STAFF

Posts: 7,350

Post Likes Received: 3,100
Date Joined: August 2013
Injury: CES
Date Injured: March 2011

Member is: Offline
Send PM

Olfactory Ensheathing Cell Transplant Apr 16, 2015 2:50:37 GMT -8

Quote

Post by Lαrα on Apr 16, 2015 2:50:37 GMT -8

capybara, Ive do believe that studies did include 'incomplete' injuries as part of the trial. Take a look at this article and see what you think.
It does seem that function return is very limited but there was improvements in the sympathetic nervous system but this mainly affects higher injury levels.

These articles are never straightforward, i need to re read it to get to the correct understanding of it!

Click here to read

capybara likes this

capybara New Member Posts: 7 Post Likes Received: 15 Date Joined: March 2015 Injury: C6 incomplete Date Injured: April 2014 Member is: Offline Send PM	Olfactory Ensheathing Cell Transplant Apr 16, 2015 11:44:10 GMT -8 Quote Select Post Deselect Post Link to Post Back to Top Post by capybara on Apr 16, 2015 11:44:10 GMT -8 Exciting news!
	DJ and Lαrα like this

Lαrα Global Moderator STAFF Posts: 7,350 Post Likes Received: 3,100 Date Joined: August 2013 Injury: CES Date Injured: March 2011 Member is: Offline Send PM	Olfactory Ensheathing Cell Transplant Apr 17, 2015 3:20:51 GMT -8 Quote Select Post Deselect Post Link to Post Back to Top Post by Lαrα on Apr 17, 2015 3:20:51 GMT -8 Apr 16, 2015 11:44:10 GMT -8 capybara said: Exciting news! Lets hope!

kilg0retr0ut Advanced Member Posts: 2,507 Post Likes Received: 1,862 Date Joined: July 2013 Injury: L4/5 Cauda Equina Date Injured: 7-15-10 Member is: Offline Send PM	Olfactory Ensheathing Cell Transplant Apr 17, 2015 4:39:01 GMT -8 Quote Select Post Deselect Post Link to Post Back to Top Post by kilg0retr0ut on Apr 17, 2015 4:39:01 GMT -8 Sooner or Later
	DJ likes this L4/5 CES

Site Map	Site Policies	Helpful Links
Home	Terms of Service	Forum Features
About Us	Privacy Policy	Site Discussion
Account	Rules	Server Status
New Posts	Report Abuse	Mobile App

Olfactory Ensheathing Cell Transplant

Post by rebeccawio on Mar 30, 2015 4:46:00 GMT -8

Post by joemonte on Mar 30, 2015 5:53:02 GMT -8

Post by DJ on Mar 30, 2015 13:59:21 GMT -8

Post by wavewolf on Apr 1, 2015 23:06:18 GMT -8

Post by rebeccawio on Apr 9, 2015 8:06:27 GMT -8

Post by capybara on Apr 15, 2015 13:08:02 GMT -8

Post by Lαrα on Apr 16, 2015 2:50:37 GMT -8

Post by capybara on Apr 16, 2015 11:44:10 GMT -8

Post by Lαrα on Apr 17, 2015 3:20:51 GMT -8

Post by kilg0retr0ut on Apr 17, 2015 4:39:01 GMT -8

Like Us On Facebook

Help Support The Forum