Pioneering Treatment of SCI in Relation to Scar Tissue
Jun 23, 2015 4:20:13 GMT -8
Post by Lαrα on Jun 23, 2015 4:20:13 GMT -8
It was so interesting to see this article this morning in regards to scar tissue and the work that is progressing in this area. The topic has been discussed within our forum recently so I appreciate the importance of this.
Dr Rafael Yáñez-Muñoz, from the School of Biological Sciences at Royal Holloway, University of London, is leading a team of researchers working to develop a novel treatment for spinal cord injury 
The project aims to develop an engineered form of chondroitinase, a bacterial protein, as a clinical therapy for SCI. Chondroitinase has been found to be one of the most promising therapeutics emerging from pre-clinical studies. Patients with SCI are prevented from recovery by the presence of excess scar tissue.
Chondroitinase efficiently breaks down scar tissue and has been shown to increase regeneration, plasticity and recovery of function in several mammalian models. Chondroitinase therefore has huge potential for translation to a clinical therapy. However, the delivery of chondroitinase to the injury site needs to be optimised. Overcoming this technical hurdle is critical for its path to the clinic – something which this project addresses
Chondroitinase efficiently breaks down scar tissue and has been shown to increase regeneration, plasticity and recovery of function in several mammalian models. Chondroitinase therefore has huge potential for translation to a clinical therapy. However, the delivery of chondroitinase to the injury site needs to be optimised. Overcoming this technical hurdle is critical for its path to the clinic – something which this project addresses
Here is the forum post where scar tissue is explained: Inspired post on Scar Tissue
Here is the link for anyone who wishes to read more: Royal Hospital of London
